Objective: To investigate the status of personal mastery during intensive treatment and analyze the influencing factors in TB patients. Methods: By convenience sampling method, 190 TB patients with intensive treatment in a Class A tertiary hospital in Tianjin were included from January to May 2021. Self-designed general data and disease-related questionnaire, Personal Mastery Scale( PMS), Acceptance of Illness Scale (AIS), Family Adaptation, Partnership, Growth, Affection and Resolve (APGAR) were used in the investigation. Univariate analysis and multiple gradual regression were used to analyze the influencing factors of personal mastery in TB patients. Results: The personal mastery of TB patients during intensive treatment is 20.0 (18.0, 21.0). Multiple linear regression analysis showed that disease acceptance, family care index, whether combing other chronic diseases, whether exercise regularly , and economic burden were influencing factors of personal mastery in TB patients during intensive treatment(P<0.05), explained 69.0% variation of personal mastery.Conclusion: The personal mastery of TB patients during intensive treatment is very unsatisfactory. Medical staff should take individualized targeted interventions to improve personal mastery, so as to improve health outcomes in TB patients.

目的：调查强化治疗期结核病患者个人掌控感现状，并分析其影响因素，为提高患者的个人掌控感和生活质量提供依据。 方法：采用便利抽样法选择 2021 年 1 月至 5 月在天津市某三级甲等医院结核科就诊的 190 例强化治疗期的患者作为研究对象。 采用自行 设计的一般资料和疾病相关资料调查表、个人掌控感量表(Personal Mastery Scale,PMS)、疾病接受度量表（Acceptance of Illness Scale, AIS）、家庭关怀度指数问卷（Family Adaptation,Partnership, Growth,Affection and Resolve,APGAR）对研究对象进行调查，采用单因素分析和多元线性回归分析患者个人掌控感的影响因素。 结果：强化治疗期结核病患者个人掌控感得分为 20.0 (18.0, 21.0)分。 多元线性回归分析显示，疾病接受度、家庭关怀指数、是否合并其他慢性疾病、是否规律锻炼和经济负担是强化治疗期结核病患者生活掌控感的影响因素(P<0．05)，共解释 69.0%的个人掌控感变异程度。 结论：强化治疗期结核病患者的个人掌控感现状不理想，医护人员应采取个体化、针对性的干预措施来提高患者个人掌控感，进而改善患者健康结局。