Objective: To evaluate the effect of follow-up nurse service on patients’ cognition behavior towards chronic hepatitis, so as to provide reference for effective prevention and control of chronic hepatitis. Methods: 98 discharged patients with chronic hepatitis were randomly divided into observation group and control group (49 in each). The patients in control group were given routine guidance only after discharged, the patients in observation group were given follow-up nurse service in addition, chronic hepatitis related knowledge, cognition behavior, quality of life and readmission rate were observed in two groups respectively. Results: After follow-up nurse service, the correct rate of related chronic hepatitis knowledge, cognition behavior and quality of life in the observation group were better than those in the control group, significant difference existed　respectively (P<0.05). Conclusion: Developing follow-up nurse service helps improve patients’ cognition behavior towards chronic hepatitis, and it is an effective way to control chronic hepatitis.

Follow-up nurse service, Chronic hepatitis, Cognition behavior