Objective: The ideological and political teaching was integrated into Nursing Research course, and evaluate its teaching effect. Methods: 121 junior nursing undergraduates in 2016 were selected as research subjects, and the curriculum ideological and political teaching reform was carried out.After the course was completed, the self-compiled Nursing Research course ideological and political learning effect questionnaire was used for evaluation. Results: The 3 ideological and political elements with the best teaching results were: integrity of college students, integrity of scientific research and medical ethics. 94.3% of the students indicated that they had established a good sense of scientific integrity through learning, and 90.9% of the students believed that they had cultivated their teamwork ability through learning. Teachers could select and determine the ideological and political elements of professional courses from the socialist core values, emotional attitude and professional literacy goals, and combine with cases to implement the ideological and political teaching. Conclusion: The curriculum ideological and political teaching of Nursing Research helps students to establish a good sense of scientific integrity, attach importance to the ethical issues of medical research, and develop their teamwork ability. However, it is necessary to further enhance the moral education ability and awareness of professional teachers, and give full consideration to the learning characteristics, cognitive rules and psychological characteristics of students, optimize teaching design, and choose appropriate ideological and political elements into the corresponding teaching chapters, and combine case analysis, task-driven teaching methods and other teaching methods as a whole to properly integrate "moral cultivation" into the teaching of professional courses.