关键词: 脓毒症, 营养状况, 相位角, 生物电阻抗技术

Abstract: Objective: To investigate the relationship between bioelectrical impedance phase angle (PA) and nutritional status of ICU patients with sepsis, and to determine the critical value of PA. Methods: A total of 98 sepsis patients admitted to ICU were selected by convenience sampling method. General information of patients was collected, and laboratory test results were recorded. Body composition analysis was performed using bioelectrical impedance technology and PA values were recorded. Malnutrition was diagnosed by Global Leadership Initiative on Malnutrition (GLIM) criteria. The receiver operating characteristic (ROC) curve of PA was drawn to find the best cut-off value, and the correlation between PA and nutrition-related indicators was analyzed. Results: Compared with the normal PA group, patients in the low PA group had a higher frequency of mechanical ventilation use and longer hospital stays, with statistically significant differences (P<0.05). PA was positively correlated with bone mineral content, skeletal muscle mass, and negatively correlated with ECW/TBW, acute physiology and chronic health evaluation II and the difference was statistically significant (P<0.05). The critical value of PA in ICU patients with sepsis was 3.25°, the area under the ROC curve was 0.631, the sensitivity was 0.632, the specificity was 0.633 and the Youden index was 0.265. Conclusion: PA is closely related to the nutritional status of ICU patients with sepsis, and the critical value of PA for predicting malnutrition is 3.25°, indicating that PA can serve as an objective screening tool for malnutrition in these patients. This provides a basis for clinical nurses to identify high-risk patients early and develops personalized nutritional support strategies.

Key words: Sepsis, Nutritional assessment, Phase angle, Bioelectrical impedance technique