天津护理 ›› 2023, Vol. 31 ›› Issue (4): 399-403.DOI: 10.3969/j.issn.1006-9143.2023.04.005

• 论著 • 上一篇    下一篇

护士主导的标准化无呕吐管理模式在头颈部鳞癌化疗患者中的应用

曹家燕 李红 陈昌连 王月阳 刘苗苗 韩旭亚   

  1. (天津医科大学肿瘤医院 国家恶性肿瘤临床医学研究中心 天津市“肿瘤防治”重点实验室 天津市恶性肿瘤临床医学研究中心,天津 300060)
  • 出版日期:2023-08-28 发布日期:2023-08-29
  • 基金资助:
    天津市卫生健康科技项目(ZC20009);天津市医学 重点学科建设项目(TJYXZDXK-011A)

Application of nurse-led standardized management program for chemotherapy-induced nausea and vomiting in patients with head and neck squamous cell carcinoma

CAO Jiayan, LI Hong, CHEN Changlian, WANG Yueyang, LIU Miaomiao, HAN Xuya   

  1. (Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060)
  • Online:2023-08-28 Published:2023-08-29

摘要:

目的:探讨护士主导的标准化无呕吐管理模式对头颈部鳞癌患者化疗所致的恶心、呕吐及生活质量的影响。 方法:选择2020 年 8 月至 2022 年 7 月接受紫杉醇联合顺铂(TP 方案)化疗的 328 例头颈部鳞癌患者,使用随机数字表法分为观察组和对照组各 164 例。 对照组接受常规化疗恶心、呕吐护理,观察组实施护士主导的标准化无呕吐管理,比较两组患者恶心、呕吐的发生率、发生程度以及对生活质量的影响。 结果:观察组患者化疗后 5 天内恶心、呕吐的发生率、恶心及呕吐的程度均低于对照 组,观察组患者生活功能指数量表恶心、呕吐维度得分均高于对照组,差异具有统计学意义(P<0.05)。 结论:护士主导的标准 化无呕吐管理可以降低头颈部鳞癌化疗患者恶心、呕吐的发生率及发生程度,降低化疗所致恶心、呕吐对患者生活质量的影响。

关键词: 头颈部鳞癌, 化学疗法, 恶心, 呕吐, 肿瘤护理

Abstract: Objective: To investigate the effect of nurse - led standardized management program on chemotherapyinduced nausea and vomiting and quality of life in patients with head and neck squamous cell carcinoma.Methods: A total of 328 patients with head and neck squamous cell carcinoma who received cisplatin-based TP regimen chemotherapy from August 2020 to July 2022 were included and randomly divided into the observation group and the control group with 164 patientsin each group. The control group received routine nursing for chemotherapy induced nausea and vomiting, and the observation group received standardized nurse-led management. The incidence, occurrence degree and influence on quality of life of patients with nausea and vomiting were compared between the two groups. Results: The incidence of nausea and vomiting, the degree of nausea and vomiting in the observation group were significantly lower than those in the control group within 5 days after chemotherapy, and the scores of the dimension of nausea and vomiting in the observation group were significantly higher than those in the control group (P< 0.05). Conclusion: Nurse-led standardized management program can reduce the incidence and degree of chemotherapy-induced nausea and vomiting in patients with head and neck squamous cell carcinoma, and reduce the influence of chemotherapy-induced nausea and vomiting on patients’ quality of life effectively.

Key words: Head and neck squamous cell carcinoma, Chemotherapy, Nausea, Vomiting, Oncologic nursing