关键词: 早期持续护理干预, 喉癌, 气管切开, 放疗, 不良反应, 依从性

Abstract:  Objective: To explore the influence of early continuous nursing intervention on the incidence of radiotherapy adverse reactions and the treatment compliance in tracheotomy patients undergo laryngeal cancer surgery. Methods: 72 tracheotomy patients were divided into observation group and control group according to the random number method. 36 patients in observation group were given early continuous nursing intervention on the basis of conventional treatment, while the other 36 patients of control group of accepted conventional care. The incidence of adverse reactions and radiotherapy compliance were compared between the two groups, such as dry mouth, oral mucositis, swallowing pain and white blood cell count during the radiotherapy. Results: The adverse reaction rates of oral mucositis, swallowing pain and leukocyte count in the observation group were lower than those in the control group (P<0.05).There was no statistically significant difference in dry mouth reaction between the observation group and the control group during the radiotherapy process (P>0.05), and the incidence of dry mouth in the observation group was lower than that in the control group at the end of radiotherapy (P<0.05).All patients in the observation group completed treatment, and the compliance with radiotherapy was significantly improved compared with the control group （P<0.05）. Conclusion: Early continuous nursing intervention can effectively reduce intensity-modulated radiation incidence of adverse reactions in tracheotomy patients during radiotherapy, can guarantee the security of radiotherapy implementation. The more important is to ensure that patients in the best time adhere to the full treatment, to improve the therapeutic compliance of patients.

Key words: Early continuous nursing intervention, Laryngeal cancer, Tracheotomy, Radiotherapy, Adverse reaction, Compliance