Abstract: Objective: To investigate the correlation of uncertainty in illness and psychosocial adaptation in patients with lung cancer during chemotherapy. Methods: Totally 175 lung cancer patients receiving chemotherapy were investigated by uncertainty in illness scale and self-report psycho-social adjustment to illness scale. Results: The mean score of uncertainty in illness was（82.84±13.47）; the mean score of psychosocial adjustment was（43.21±8.52）. The total score and factor scores of uncertainty in illness were negatively correlation with the total score of psychosocial adjustment (r=-0.183～-0.932，P<0.05). Conclusion: Lung cancer patients’ uncertainty in illness is negatively correlated with their psychosocial adjustment. Nurses should take appropriate intervention programs to reduce the level of patient’s uncertainty in illness, improve the negative emotions of patients, rebuild and social relation, their psychological and social adaptability.

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摘要： 目的：探讨肺癌化疗患者疾病不确定感与心理社会适应的相关性。方法：采用一般资料调查表、肺癌患者疾病不确定感量表和疾病心理社会适应量表对175名化疗期的肺癌患者进行调查。结果：肺癌化疗患者的疾病不确定感总分为（82.84±13.47）分；心理社会适应能力总分为（43.21±8.52）分；两者总分及各维度之间呈负相关（r=-0.183～-0.932，P<0.05）。结论：肺癌化疗患者疾病不确定感与心理社会适应呈负相关，随着疾病不确定感水平的增加，其心理社会适应越低。护理人员应采取适当的干预方案加强对疾病的认知，降低患者的疾病不确定感水平，鼓励患者积极参加疾病治疗过程，帮助其适应角色转变，促进疾病的心理适应过程。

关键词: 肺癌, 化疗, 疾病不确定感, 心理社会适应