Objective: To systematically evaluate the risk factors of implantable venous access port related thrombosis in tumor patients by meta -analysis. Methods: PubMed, Cochrane Library,Web of Science, Embase, CBM, CNKI, WanFang Data and VIP database were retrieved from the inception to April 1st，2021. Two researchers independently screened the literature and extracted the data. The RevMan 5.3 software was used for meta-analysis. Results: A total of 17 literatures with 25 risk factors were included. Meta-analysis of results showed that risk factors of implantable venous access port-related thrombosis in tumor patients including age≥60(OR=0.30, 95% CI 0.13～0.70) ,BMI≥24 kg/m² (OR=0.60, 95% CI 0.47～0.76), infection (OR=6.34, 95% CI 1.38～29.11) ,thrombosis history(OR=3.41, 95% CI 1.63～7.14), tumor stage III ~ IV (OR=0.47, 95% CI 0.26～0.85), gastrointestinal carcinoma of tumor classification(OR=0.68, 95% CI 0.56～0.83), TEC(OR= 4.13, 95% CI 1.38～12.34)，surgical history(OR=1.43, 95%CI 1.06～1.92)，and port tip location(OR=0.15, 95%CI 0.07～0.32).Conclusion: The results of this study showed that age, BMI, infection, history of thrombosis, tumor stage, tumor classification, chemotherapy regimen, surgical history, and port tip location were the risk factors of implantable venous access portrelated thrombosis. Medical staffs should increase the management of risk factors in clinical nursing of implantable venous access port to prevent thrombosis.

目的： 采用 Meta 分析方法， 系统评价肿瘤患者植入式输液港相关血栓发生的危险因素。 方法： 通过计算机检索 PubMed、Cochrane Library、Web of Science、Embase、医学文献数据库（CBM）、中国知网（CNKI）、万方数据库（WanFang Data）和维普数据库(VIP) 中与肿瘤患者输液港相关血栓发生危险因素的研究。 检索时限均为建库至 2021 年 4 月 1 日。 由 2 名研究者独立筛选文献、提取资料，并对文献进行质量评价。 采用 RevMan 5.3 软件进行 Meta 分析。 结果：共纳入 17 篇文献，25 项危险因素。 Meta 结果分 析显示：年龄≥60 岁（OR=0.30，95% CI 0.13～0.70）、体质量指数（BMI）≥24 kg/m² （OR=0.60，95% CI 0.47～0.76）、感染（OR=6.34，95%CI 1.38～29.11）、血栓史（OR=3.41，95% CI 1.63～7.14）、肿瘤分期中 III~IV 期（OR=0.47，95% CI 0.26～0.85）、肿瘤分型中胃肠癌（OR= 0.68，95% CI 0.56～0.83）、化疗方案中 TEC（OR=4.13，95% CI 1.38～12.34）、手术史（OR=1.43，95% CI 1.06～1.92）、导管尖端位置位于 上腔静脉以上（OR=0.15，95% CI0.07～0.32）是肿瘤患者输液港相关血栓形成的危险因素。 结论：年龄、BMI、感染、血栓史、肿瘤分 期、肿瘤分型、化疗方案、手术史和导管尖端位置是输液港相关血栓发生的危险因素，医护人员在临床护理输液港工作中应加大对 危险因素管理，预防血栓发生。