Abstract: Objective: To identify the clinical value of hospital anxiety and depression scale(HAD) in screening anxiety and depression of patients with chronic obstructive pulmonary disease(COPD) and test its reliability and validity. Methods: 200 cases of patients with COPD hospitalized were enrolled by cross-sectional study. Then questionnaires were performed and analyzed. Results: The study of 189 valid questionnaires showed that the two subscales of HADS had significantly correlations with the self-rating anxiety scale(SAS) and the self-rating depression scale(SDS)(P<0.01). Taking SAS and SDS as the gold standard, the area under of the receiver operating characteristic curve(ROC) of both subscale were 0.823（95%CI：0.752~0.881）and 0.906（95%CI：0.847~0.948）, respectively. The Cronbach’s alpha coefcients of HADS and two subscales had been found to be 0.89, 0.76, 0.83 respectively. Conclusion: The HADS could help clinical medical staffs improve the screening efficiency of bad mood as a reliable and valid instrument for the assessment of anxiety and depression in patients with COPD.

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目的：探讨医院焦虑抑郁量表在慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）患者焦虑、抑郁情绪筛查中的应用价值，并评估其信度和效度。方法：应用横断面研究方法，选择COPD住院患者200例，对其进行问卷调查。结果：获得有效问卷189份。医院焦虑抑郁量表（HADS）中焦虑、抑郁亚量表得分分别与焦虑自评量表、抑郁自评量表得分呈正相关（P<0.01）；以焦虑自评量表和抑郁自评量表作为诊断“金标准”分别绘制焦虑亚量表和抑郁亚量表的ROC曲线，其曲线下面积分别为0.823（95%CI：0.752~0.881）和0.906（95%CI：0.847~0.948）；医院焦虑抑郁量表总表、焦虑亚量表及抑郁亚量表的内部一致性系数的Cronbach's α分别为0.89, 0.76, 0.83；HADS得分水平与生活质量指数量表呈负相关，证明了其构念效度（P<0.05）。结论：医院焦虑抑郁量表可以可靠、有效地筛查COPD患者的焦虑、抑郁情绪，可以提高临床医务人员对患者不良情绪的筛查效能。

关键词:  ,  ,  , 慢性阻塞性肺疾病, 焦虑, 抑郁, 医院焦虑抑郁量表