Abstract:  Objective: To analyze the fear of disease progress, positive and negative emotional state in patients with cirrhosis and gastrointestinal bleeding, and explore the relationship between them.Methods: A total of 101 patients with cirrhosis and gastrointestinal bleeding from March 2018 to June 2019 intwo third-class A hospitals in Tianjin were selected as the study subjects. The status of patients was investigated by using the general data questionnaire, simplified scale of fear of disease progression scale (FoPQ-SF)， positive and negative emotional experience scale(PANAS), and Pearson correlation analysis was used to explore the relationship. Results:The total score of FoPQ-SF in patients with liver cirrhosis and gastrointestinal hemorrhage was 34.95±7.05.The scores of physiological health dimension and social family dimension were （20.25±4.79）, （14.69±2.61）, respectively. The total score of 53 patients was more than 34 (52.5% of the patients). The score of positive emotional experience and the negative emotional experience were（28.58±5.03）,（24.65±5.7），respectively.Pearson correlation analysis results showedthat positive emotional experience was negatively correlated with the fear of disease progression (r=-0.272, P<0.05), and negative emotional experience was positively correlated with it(r=0.577, P<0.05).Conclusion:The patients with cirrhosis and gastrointestinal bleeding had a higher level of fear of disease progression. The patients who have higher positive emotional experience have the lower level of negative emotionaland the fear of disease progress.

Key words: Cirrhosis, Gastrointestinal hemorrhage, Fear of disease progression, Negative emotion

摘要： 目的：调查并分析肝硬化合并消化道出血患者恐惧疾病进展和正负性情绪状态现状，并探讨两者相互关系。方法：选择2018年3月至2019年6月天津市某2所三级甲等医院肝硬化合并消化道出血患者共101例，采用一般资料调查表、恐惧疾病进展量表简化量表（FoPQ-SF）、正性负性情绪体验量表（PANAS）进行现况调查，采用Pearson 相关性分析进行相互关系探讨。结果：肝硬化合并消化道出血患者恐惧疾病进展总分（34.95±7.05）分，生理健康维度（20.25±4.79）分，社会家庭维度（14.69±2.61）分，其中共53例患者总分≥34分，占总人数的52.5%；正性情绪体验（28.58±5.03）分，负性情绪体验（24.65±5.72）分；Pearson相关性分析结果显示，正性情绪体验与恐惧疾病进展成呈负相关（r=-0.272,P<0.05），负性情绪体验与恐惧疾病进展呈正相关（r=0.577,P<0.05）。结论：肝硬化合并消化道出血患者恐惧疾病进展处于较高水平，其正性情绪体验越高，负性情绪水平越低者，其恐惧疾病进展越低。

关键词: 肝硬化, 消化道出血, 恐惧疾病进展, 负性情绪