Abstract: Objective:To systematically evaluate the Clinical efficacy of traditional Chinese medicine fumigation in the treatment of shoulder hand syndrome. Methods: Literature search was conducted in such databases as Cochrane Library,EMbase,PubMed,CNKI,CBM,WanFang Data and VIP from the dates of establishment to March 2018. Two reviewers independently screened the literature according to the inclusion and exclusion criteria, extracted the data and assessed the risk of bias of included studies. Then, meta-analysis was performed using RevMan 5.3 sofware. Results:A total of 13 studies involving 880 patients were included. The results of meta-analysis showed that the Traditional Chinese medicine fumigation group was superior to the control group in effectiveness［RR=1.23，95%CI（1.15，1.32），P<0.01］, FMA score［MD=8.1，95%CI（4.95，11.25），P<0.000 01］，VAS score［MD=-1.74，95%CI（-2.23，-1.25），P<0.01］，shoulder mobility ［MD=-0.64，95%CI（-0.89，-0.38），P<0.01］，with statistically signifcant differences. However, There was no statistically difference in subgroup of FMA scores intervention in 2~3 weeks between the two groups［MD= 7.02，95%CI（-1.00，15.05），P=0.09］.Conclusion:Chinese medicine fumigation can improve the upper extremity motor function of patients with shoulder hand syndrome, relieve pain and improve shoulder mobility. However, due to the limitation of quality and quantity of the included studies, this aforementioned conclusion should be further verified by conducting more large-scale high quality RCTs.

Key words: Traditional Chinese medicine fumigation, Shoulder hand syndrome, Systematic review, Meta-analysis, Randomized controlled trial

摘要： 目的：系统评价中药熏蒸治疗肩手综合征的临床疗效。方法：计算机搜索The Cochrane Library、EMbase、PubMed、CNKI、CBM、WanFang Data及VIP 数据库，寻找中药熏蒸治疗肩手综合征的随机对照试验（RCT），搜索时间范围从数据库构建到2018年3月。由2位评估员根据纳入与排除标准独立进行文献筛选、资料提取及纳入研究的偏倚风险评估后，使用RevMan5.3软件进行Meta分析。结果：最终纳入13个研究，共880名患者。Meta分析结果显示：中药熏蒸组在治疗有效率［RR=1.23，95%CI（1.15，1.32），P＜0.01］、FMA评分［MD= 8.1，95%CI（4.95，11.25），P＜0.01］、VAS评分［MD= -1.74，95%CI（-2.23，-1.25），P＜0.01］及肩关节活动度［MD =-0.64，95%CI（-0.89，-0.38），P＜0.01］方面优于对照组，差异均有统计学意义；但两者在FMA评分的亚组干预2～3周中差异无统计学意义［MD= 7.02，95%CI（-1.00，15.05），P=0.09］。结论：中药熏蒸可以改善肩手综合征患者的上肢运动功能，减轻疼痛，改善肩关节活动度。由于所包含研究的数量和质量的限制，需要更多的大样本高质量研究来验证上述结论。

关键词: 中药熏蒸, 肩手综合征, 系统评价, Meta 分析, 随机对照试验