Objective: To evaluate the effects of nutrition management manual on postoperative nutritional status and disease recovery in patients with laryngeal cancer. Methods: A total of 89 laryngeal cancer patients with nutritional risk rated by NRS-2002≥ 2 nutritional screening were divided into an experimental group(n＝43）and a control group(n＝46）. The patients in experimental group received nutritional intervention with nutrition management manual before the operation, while the patients in control group received routine dietary guidance. The biochemical measurement of postoperative nutritional status, BMI, hospital stays and postoperative complications were compared between the two groups. Results: The levels of pre-albumin, total protein and BMI one day before the operation and one week after the operation in the experimental group were significantly higher than those in the control group(P＜0.05 ). There was no significant difference in the rate of postoperative complications between the two groups(P>0.05 ). The hospital stay time was shorter than that of the control group, and the difference was statistically significant(P>0.05). There was no significant difference in the level of albumin between the two groups at one week after the operation(P>0.05). Conclusion: By applying nutrition management manual to preoperative patients with laryngeal cancer, the nutritional status and BMI of patients can be improved and the length of hospitalization can be shortened.