关键词: 肺癌, 中青年, 工作生活质量, 自我调节疲劳, 社会支持

Abstract: Objective: To explore the mediating role of social support on self-regulated fatigue and quality of working life. Methods: Participants were selected from young and middle-aged postoperative lung cancer patients which returned to work for ≥1 month in a cancer hospital with Grade A，Level 3 in Tianjin. This study was conducted using convenience sampling. Questionnaire survey was conducted using the general information questionnaire，Self-regulated Fatigue Scale，Perceived Social Support Scale，and Quality of Working Life Questionnaire for Cancer Survivors. The data analysis were performed by SPSS 22.0 and Process plug-in. Results: The mean score of Quality of Working Life Questionnaire for Cancer Survivors for all participants was 51.93±24.31. Pearson correlation analysis showed that the working life quality was negatively correlated with self-regulated fatigue(r=-0.133，P<0.05) and positively correlated with social support(r= 0.319，P<0.01) in young and middle-aged lung cancer patients. Bootstrap analysis indicated that social support played a complete mediating role on self-regulated fatigue and working life quality，with a mediating effect size of -0.251(95%CI -0.529~-0.011；P<0.05). The intermediate effect accounted for 34.813% of the total effect. Conclusion: The quality of working life of young and middle-aged adults with postoperative lung cancer patients needed to be improved and social support can play a completely mediating role in self-regulated fatigue and working life quality. It′s indicated that family，society and medical staff should actively take measures as soon as possible，and carry out personalized continuing nursing interventions to improve the quality of working life.

Key words: Lung cancer, Young and middle aged adults, Quality of working life, Self-regulated fatigue, Social support