关键词: 肝癌, 介入治疗, 疼痛灾难化, 影响因素

Abstract: Objective: To investigate the status of pain catastrophizing and its influencing factors in liver cancer patients after interventional therapy. Methods: Using a convenience sampling method, patients receiving interventional therapy for liver cancer from a tertiary Grade A hospital in Tianjin were selected as survey participants between December 1, 2023, and June 30, 2024. Surveys were conducted using the General Information Questionnaire, the Pain Catastrophizing Scale, the Generalized Anxiety Disorder Scale, the Patient Health Questionnaire-9, the 10-item Conner-Davidson Resilience Scale, the Distress Thermometer, and the Fear of Progression-Short Form. Results: The pain catastrophizing score of patients undergoing interventional therapy for liver cancer was 31.30±9.86. Multiple linear regression analysis showed that post interventional pain history, gender, fear of progression, anxiety, psychological distress, and psychological resilience were significant influencing factors of pain catastrophizing in this patient population (all P<0.05). A total of 32.9% of the variation was explained. Conclusion: Patients undergoing interventional therapy for liver cancer have a high level of pain catastrophizing. It is necessary to pay attention to those with a history of post-interventional pain, female, those presenting with heightened fear of disease progression, elevated anxiety, increased psychological distress, or diminished psychological resilience. Early assessment and targeted interventions for these individuals are essential to effectively reduce the level of pain catastrophizing.

Key words: Liver cancer, Interventional therapy, Pain catastrophizing, Influencing factors