Abstract: Objective: To analyze the risk factors for preoperative deep vein thrombosis (DVT) in patients with osteoporotic vertebral fractures. Methods: A retrospective analysis was conducted on clinical data from 346 hospitalized patients with osteoporotic vertebral fractures. Based on preoperative DVT diagnostic results, patients were divided into a DVT group (n= 34) and a non-DVT group (n=312). Univariate and multivariate logistic regression analyses were used to identify preoperativerisk factors for DVT. Results: The incidence of DVT among the 346 patients with osteoporotic vertebral fractures was 9.8%. Logistic regression analysis revealed that body mass index (BMI), D-dimer, and C-reactive protein (CRP) were significant risk factors for DVT. D-dimer demonstrated high predictive sensitivity and specificity. Conclusion: Elevated levels of BMI, D-dimer, and CRP are closely associated with preoperative DVT. Monitoring these indicators facilitates early identification of high-risk patients, enabling timely preventive and interventional measures to optimize preoperative management and reduce complications.

Key words: Osteoporosis vertebral fracture, Deep vein thrombosis, Risk factors

摘要： 目的：分析骨质疏松性椎体骨折患者术前发生深静脉血栓形成（Deep Vein Thrombosis，DVT）的危险因素。方法：回顾性分析 346 例骨质疏松性椎体骨折住院患者的临床资料，按照患者术前 DVT 的诊断结果将其分为 DVT 组（n=34）和非 DVT 组（n=312），采用单因素及多因素 Logistic 回归分析术前 DVT 的危险因素。结果：346 例骨质疏松性椎体骨折患者 DVT 发生率为 9.8%。Logistic 回归分析结果显示，身体质量指数（BMI）、D -二聚体（D-dimer）、C 反应蛋白（CRP）是骨质疏松性椎体骨折患者深静脉血栓形成的危险因素，D -二聚体具有较高的预测灵敏度和特异度。结论：BMI、D-dimer 和 CRP 水平与术前 DVT 的发生密切相关，关注这些指标变化有助于早期识别 DVT 高风险患者，以便及时采取预防和干预措施，优化患者的术前管理，减少并发症的产生。

关键词: 骨质疏松性椎体骨折, 深静脉血栓形成, 危险因素