关键词: 糖尿病足溃疡, 分级管理, 预防, Meta分析

Abstract: Objective:To systematically evaluate the effect of risk stratification management on preventing diabetic foot ulcer.Methods:Randomized Clinical Trials（RCTs） that assessed the effectiveness of risk stratification management in patients with diabetes foot ulcer were systematically reviewed using multiple electronic databases.Strict literature quality evaluation was conducted with reference to Cochrane handbook 5.1.0, and meta-analysis was conducted with RevMan5.3 software. Results: 8 RCTs and 1295 patients were included. Compared with the control group, the risk classification management model reduced the occurrence of diabetic foot ulcer by 3%, and the difference was statistically significant[RD=-0.03, 95%CI(-0.05,0.00), P=0.04].The arterial ankle brachial index(ABI) was higher than those of the control group (P<0.001). The motor nerve conduction velocity[MD=3.53, 95%CI (2.02,5.05), P<0.01] and sensory nerve conduction velocity[MD=4.53, 95%CI(2.93,6.13), P<0.01] were significantly superior to control group. Conclusion: Compared to routine health management, the risk stratification management model can effectively prevent diabetic foot ulcer and improve the status of patients’ arteries and peripheral nerves.

Key words:  , Diabetic foot ulcer, Stratification management, Prevention, Meta-analysis