关键词: 家族聚集性, 肝癌, 配偶, 疾病不确定感, 希望, 焦虑

Abstract: Objective: To investigate the status of disease uncertainty and its association with hope and anxiety among spouses of liver cancer patients who were diagnosed as family aggregation of liver cancer, so as to provide theoretical basis for nursing staffs to help spouses reduce disease uncertainty. Methods: Convenient sampling method was used to recruit 200 spouses of liver cancer patients who had family aggregation of primary liver cancer. Measurement tools included a self-designed general data questionnaire, Mishel Uncertainty in Illness Scale-Family Member Form, Herth Hope Scale and Zung Self-Anxiety Scale. Results: The mean score of disease uncertainty of spouses was 64.17±11.61, which was at a medium level, and the mean score of hope was 38.39±4.59, and the mean score of anxiety was 37.09±8.76. The results of single-factor analysis showed that spouses with different age, and education qualifications had different scores of disease uncertainty (P<0.05). Correlation analysis showed that disease uncertainty was negatively associated with hope (r=-0.447, P<0.001), and was positively associated with anxiety(r=0.252, P<0.001). Conclusion: The disease uncertainty of the spouses was at a medium level, and the hope was at a high level. Parts of spouses were anxious about the patients’ disease. It is highly recommended that nurses should provide personalized and targeted information and education to the spouses of liver cancer patients who were diagnosed as family aggregation of liver cancer, so as to assist with reducing their sense of disease uncertainty and improving their sense of hope.