关键词: 晚期原发性肝癌, 死亡焦虑, 心理应激, 家庭关怀, 症状负担

Abstract: Objective: To explore the status and influencing factors of death anxiety in patients with advanced primary liver cancer, to provide the reference for the end-of-life care of patients with advanced primary liver cancer. Methods: Using convenience sampling method, 190 patients with advanced primary liver cancer from January 2022 to May 2023 were included. The survey was conducted using a general information questionnaire, death anxiety scale, psychological stress scale, family care scale, and disease burden scale. Pearson correlation analysis was used to analyze the correlation between death anxiety, psychological stress, and family care, multiple linear regression analysis was used to analyze the factors that affect the level of death anxiety. Results: The score of patients with advanced primary liver cancer was 7.79±1.57, indicating a high level of death anxiety. The score of psychological stress was 92.73±11.33, indicating a high level of psychological stress. The score of family care was 2.54±0.36, indicating a low level of lack of family care. The total score of disease burden was 7.39±1.15, indicating a severe disease burden. Pearson correlation analysis showed that the total score and dimensions of death anxiety were positively correlated with psychological stress and disease burden (P<0.05), while the total score and dimensions of death anxiety were negatively correlated with the total score of family care (P<0.05). Multiple linear regression analysis showed that religious belief, children′s situation, symptom burden, psychological stress, and family care were the influencing factors of death anxiety in patients with advanced primary liver cancer (P<0.05). Conclusion: The high level of death anxiety in advanced primary liver cancer patients is closely related to psychological stress and family care. Religious belief, children′s condition, symptom burden, psychological stress and family care as risk factors affecting the level of death anxiety should be paid attention to during clinical intervention.

Key words: Advanced primary liver cancer, Death anxiety, Psychological stress, Family care；Symptom burden