关键词: 中青年患者, 银屑病, 外用药依从性, 影响因素

Abstract: Objective: To explore the status quo and influencing factors among young and middle-aged patients with psoriasis who receive maintenance treatment with topical medications according to the prescribed course, and to provide a reference for further formulation of targeted nursing measures. Methods: Using the convenience sampling method, the young and middle-aged psoriasis patients who visited the dermatology department of a tertiary grade A hospital in Tianjin from October 1, 2022 to October 20, 2023 were selected as the research subjects. General information questionnaire, Morisky medication compliance evaluation scale, social appearance anxiety scale (SAAS) and social support rating scale were used for the investigation. Logistic regression model was employed to analyze the influencing factors. Results: Among the subjects, 201 (62.42%) had good compliance. Multivariate analysis showed that social appearance anxiety score, psoriasis comorbidities, types of combined drugs and adverse drug reactions were the main influencing factors for the compliance of young and middle-aged patients with psoriasis. Conclusion: The medication compliance of psoriasis in young and middle-aged patients is at a moderate level. Attention should be paid to patients with low level of social appearance anxiety, more comorbidities, more types of combined drugs and severe adverse drug reactions. Targeted measures such as strengthening health education, continuous follow-up and reducing adverse drug reactions should be taken to improve the compliance of external drugs and promote the therapeutic effect.

Key words: Middle-aged and young patients, Psoriasis, Compliance of external medication, Influencing factor