高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为
智能发育及后遗症的影响

doi:10.3969/j.issn.1006-9143.2022.01.011

天津护理 ›› 2022, Vol. 30 ›› Issue (2): 169-173.DOI: 10.3969/j.issn.1006-9143.2022.01.011

高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为智能发育及后遗症的影响

王晶¹ 张晓玲¹ 董悦²

（1.江苏省建湖县人民医院，江苏盐城 224700；2. 江苏省建湖县第二人民医院）

出版日期:2022-04-28 发布日期:2022-04-28

The effect of hyperbaric oxygen combined with early comprehensive rehabilitation on the behavior and intelligence development and sequela of premature infants with hypoxic-ischemic encephalopathy

WANG Jing¹, ZHANG Xiaoling¹, DONG Yue²

(1. The People’s Hospital of Jianhu, Jiangsu Province, Jiangsu Yancheng 224700;2.The Second People’s Hospital of Jianhu, Jiangsu Province)

Online:2022-04-28 Published:2022-04-28

摘要/Abstract

摘要： 目的：探讨高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为智能发育及后遗症影响。方法：选择2018年4月至2020年4月收治的缺氧缺血性脑病（HIE）早产儿100例，随机分为对照组（n=33）、研究A组（n=33）、研究B组（n=34）。对照组患儿接受常规对症支持治疗，在对照组基础上研究A组同时进行高压氧治疗，研究B组患儿同时进行高压氧治疗与早期综合康复护理干预，评估并比较3组患儿行为智能发育情况及神经系统后遗症发生情况。结果：研究A组、B组患儿14日龄、28日龄神经行为发育评估（NBNA）得分均高于对照组，3月龄、6月龄心理运动发育指数（PDI）与智力发育指数（MDI）均高于对照组，12月龄时社交、语言、大动作、精细动作等能区的发育商（DQ）评分均高于对照组，且后遗症发生率低于对照组，差异有统计学意义（P<0.05）。研究B组患儿14日龄、28日龄NBNA得分均高于研究A组，3月龄、6月龄PDI指数与MDI指数均高于研究A组，12月龄时社交、语言、大动作、精细动作等能区DQ 评分均高于研究A组，差异有统计学意义（P<0.05）。结论：高压氧配合早期综合康复护理可改善缺血性脑病早产儿神经系统功能，促进神经行为发育与智能发育，降低后遗症发生率。

关键词: 高压氧, 康复护理, 缺氧缺血性脑病, 早产儿, 神经行为发育, 智能发育, 后遗症

Abstract: Objective: To analyze the effects of hyperbaric oxygen combined with early comprehensive rehabilitation measures on promoting behavior and intelligence development in preterm infants with hypoxic-ischemic encephalopathy and the effects on sequela. Methods: A total of 100 cases of HIE premature infants admitted in the hospital from April 2018 to April 2020 were included and were randomly divided into control group(n=33), intervention group A (n=33) and intervention group B (n=34). Children in the control group received routine symptomatic supportive treatment. Intervention group A received hyperbaric oxygen therapy based on control group, and intervention group B received hyperbaric oxygen therapy combined with early comprehensive rehabilitation based on control group. Behavior and intelligence development and the occurrence of neurological sequelae were evaluated and compared between different groups. Results: The NBNA scores of the 14-day and 28-day after birth in intervention group A and B were significantly higher than those of the control group, and the PDI index and MDI index were significantly higher than those of the control group at 6 and 12 months after birth. The DQ scores of language, motor and fine motor areas were significantly higher than those of the control group and the incidence of sequela was significantly lower than those of the control group at 12 months after birth (P<0.05).The NBNA scores of the 14-day and 28-day after birth in intervention group B were higher than those in intervention group A, and the PDI index and MDI index were higher than those in intervention group A at 3 months and 6 months after birth. The DQ scores of language, motor and fine motor areas in intervention group B were significantly higher than those of the intervention group A(P<0.05). Conclusion: Hyperbaric oxygen combined with early comprehensive rehabilitation measures can improve neurological function and promote neurobehavioral development and intelligent development, meanwhile, reduce the incidence of sequela in preterm infants with ischemic encephalopathy.

Key words: Hyperbaric oxygen, Early comprehensive rehabilitation, Hypoxic ischemic encephalopathy, Premature infant, Neurobehavioral development, Intelligent development, Sequela

王晶张晓玲董悦 . 高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为智能发育及后遗症的影响[J]. 天津护理, 2022, 30(2): 169-173.

WANG Jing, ZHANG Xiaoling, DONG Yue. The effect of hyperbaric oxygen combined with early comprehensive rehabilitation on the behavior and intelligence development and sequela of premature infants with hypoxic-ischemic encephalopathy[J]. Tianjin Journal of Nursing, 2022, 30(2): 169-173.

[1]	吴佳倩黄素群李敏毕科. 高压氧辅助治疗压力性损伤疗效的Meta分析[J]. 天津护理, 2022, 30(4): 418-421.
[2]	冷静张学颖. 一例早产儿合并先天性白内障围手术期护理[J]. 天津护理, 2021, 29(1): 115-118.
[3]	储玲玲张琴汪丽平 . 口腔运动干预在促进早产儿经口喂养中的应用现状[J]. 天津护理, 2021, 29(1): 124-126.
[4]	程玥, 张海然, 邓珺文. 一例复杂先天性心脏病早产儿术后应用体外膜肺氧合的护理[J]. 天津护理, 2020, 28(6): 726-728.
[5]	胡祥芹隋爱慈何冬丽. 基于Citespace的国内早产儿喂养不耐受研究的可视化分析[J]. 天津护理, 2020, 28(2): 160-162.
[6]	龚晨王光鹏乔建歌周丹杨青敏. 老年脑卒中患者吞咽障碍康复护理研究现状[J]. 天津护理, 2019, 27(6): 742-744.
[7]	马恩婷郑嘉祺魏力. 天津市社区卫生服务机构康复护理资源配置现状分析[J]. 天津护理, 2019, 27(5): 559-561.
[8]	李慧英. 髋臼周围截骨术治疗大龄儿童髋关节发育不良的康复护理[J]. 天津护理, 2019, 27(4): 437-439.
[9]	裔欣李颖王烨明. Philos钢板加腓骨棒植入治疗肱骨近端骨折伴骨质疏松患者的康复护理[J]. 天津护理, 2019, 27(2): 214-216.
[10]	于起苹魏佳丽刘长英. 分阶段康复护理对急性脑梗死溶栓后患者康复效果的影响[J]. 天津护理, 2019, 27(1): 48-51.
[11]	刘永戍沈婷聂玲俞建文. 延续性护理在早产儿出院后管理中的应用效果观察[J]. 天津护理, 2018, 26(6): 665-667.
[12]	郑嘉祺1 柴倩文2 魏力1. 社区老年康复护理核心知识体系的构建*[J]. 天津护理, 2018, 26(6): 672-676.
[13]	陈赛钗丁敏芳游琼. 微信平台在帕金森病患者出院后延续康复护理中的应用*[J]. 天津护理, 2018, 26(6): 694-697.
[14]	杨永芬王铭刘会欣李海滨代娟杨学桥. 腕关节镜下韧带重建术治疗下尺桡关节不稳患者的康复护理[J]. 天津护理, 2018, 26(2): 225-226.
[15]	宋爱军. 阿尔茨海默病护理现状[J]. 天津护理, 2018, 26(2): 247-249.

高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为智能发育及后遗症的影响

The effect of hyperbaric oxygen combined with early comprehensive rehabilitation on the behavior and intelligence development and sequela of premature infants with hypoxic-ischemic encephalopathy

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为 智能发育及后遗症的影响

The effect of hyperbaric oxygen combined with early comprehensive rehabilitation on the behavior and intelligence development and sequela of premature infants with hypoxic-ischemic encephalopathy

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为智能发育及后遗症的影响