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The investigation on influence factor of morning blood pressure surge in the elderly patients with COPD and hypertension undergoing invasive ventilation

  

  1. School of Nursing, Tianjin Medical University, Tianjin 300070
  • Received:2018-01-12 Online:2018-04-28 Published:2018-05-08

有创通气下COPD合并高血压老年患者血压晨峰的观察及影响因素分析

  

  1. 天津医科大学护理学院,天津    300070
  • 作者简介:作者简介:王乔硕,女,主管护师,硕士在读 通信作者:赵 岳,男,教授,院长,博士

Abstract:  

Objective: To investigate the situation and risk factors of morning blood pressure surge by analyzing of 24h dynamic blood pressure in the elderly patients with COPD and primary hypertension undergoing invasive mechanical ventilation. Methods:79 cases of elderly patients with COPD and primary hypertension under invasive mechanical ventilation( SIMV ventilation mode, PEEP≤5cmH2O) were selected in the respiratory intensive care unit of a top three hospital in Tianjin. EKG and APACHEⅡ were used to monitor 24h ambulatory blood pressure and to assess condition of the patients. Results: The average of 24h systolic blood pressure(24h SBP) was 151.20±5.69 mmHg,and the average of 24h diastolic pressure(24h DBP) was 76.39±6.42 mmHg. About 72.2% of the patients have high-morning blood pressure surge, and the average of morning blood pressure surge was 38.82±8.78 mmHg. Single factor analysis showed that there were differences in morning blood pressure surge between patients with different age and different APACHE II score, and there was statistic difference in the average of 24h SBP and D-SBP(diurnal systolic blood pressure) between the patients with morning surge arose or not;Logistic regression analysis showed that APACHE II score, the average of 24h SBP and D-SBP were the influence factors of the morning surge arose, the three could explain 82.3% of the blood pressure variation.Conclusion: The proportion of morning surge cases in the elderly patients with COPD and primary hypertension undergoing invasive ventilation is higher. We should pay more attention on the patients with critical condition of morning surge arose in order to relive the damages to target organ.

Key words: Chronic obstructive pulmonary disease(COPD), Hypertension, Morning blood pressure surge, Invasive ventilation, Elderly patient

摘要: 目的:分析有创通气下COPD(Chronic Obstructive Pulmonary Disease,COPD)合并原发性高血压老年患者24 h动态血压情况,探讨血压晨峰的特点及晨峰高血压现象的影响因素。方法:选取天津市某三甲医院呼吸与危重症监护病房住院的有创通气治疗(均为SIMV通气模式,PEEP≤5 cmH2O)的COPD合并原发性高血压老年患者,采用心电监护仪(EKG)进行24 h动态血压监测并记录血压数据,采用APACHEⅡ评估患者入呼吸与危重症监护病房时的病情情况。结果:共纳入79例患者, 24 h收缩压(24 h SBP)均值为(151.20±5.69)mmHg(1 mmHg=0.133 kPa),24 h DBP(24 h舒张压)均值为(76.39±6.42)mmHg,约72.2% 的患者具有晨峰高血压现象,血压晨峰均值为(38.82±8.78) mmHg;单因素分析显示,不同年龄、APACHEⅡ得分不同的患者间血压晨峰存在差异,是否具有晨峰高血压现象的患者间24 h SBP均值、d SBP均值存在统计学差异;Logistic回归分析显示 APACHEⅡ评分、24 h SBP均值、d SBP均值是晨峰高血压现象的影响因素,三者可解释血压变异的82.3% 。结论:有创通气下的COPD合并原发性高血压老年患者中晨峰高血压现象的比例较高;临床护理时应加强对具有晨峰高血压现象患者的鉴别,为降低晨峰高血压对靶器官损害的护理措施的实施提供依据。

关键词: COPD, 高血压, 血压晨峰, 有创通气, 老年患者