Abstract: Objective: To investigate the status of frailty in senile patients with acute coronary syndrome(ACS) after percutaneous coronary intervention(PCI) and analyze the influencing factors, so as to provide reference and basis for formulating holistic nursing measures and management plans for them. Methods: 202 elderly patients with ACS after PCI in Tianjin from January 2018 to June 2019 were selected. A cross-sectional survey was conducted using the general population questionnaire and the Chinese version of the senile weakness assessment scale. Analysis of variance and multiple linear regression were used to analyze the influencing factors. Results: The total frailty score of senile patients with ACS was 9.46±2.36, and the incidence of frailty was 61.4%. The results of multiple linear regression showed that age, exercise habit, self-care ability, smoking, multiple diseases, TC, Hb, Alb and WBC were independent influencing factors of weakness (P<0.05), which explained 61.4% of the total variance of weakness degree. The regression model had statistical significance (F=21.033, P<0.01). Conclusion: Elderly patients with ACS have higher levels of frailty. It is important to timely assessment and identification of patients’ weakness status, early intervention to prevent or reduce the frailty status of senile patients with ACS.

Key words: Acute coronary syndrome, Percutaneous coronary intervention (PCI), Frailty, Influence factors

摘要： 目的：调查老年急性冠脉综合征PCI术后患者的衰弱现状，并分析其影响因素，为老年急性冠脉综合征PCI术后患者制定整体护理措施和管理计划提供参考和依据。方法：选择2018年1月至2019年6月老年急性冠脉综合征PCI术后患者202例，采用一般资料调查表、中文版老年人衰弱评估量表进行横断面调查，采用方差分析和多元线性回归进行影响因素分析。结果：老年急性冠脉综合征患者衰弱总分（9.46±2.36）分，衰弱发生率为61.4%；多元线性回归结果显示，年龄、运动习惯、自理能力、吸烟、多病共存、总胆固醇(TC)、血红蛋白(Hb)、白蛋白(Alb)、白细胞(WBC)是衰弱的独立影响因素（P<0.05），共解释衰弱程度总变异度的61.4%；回归模型具有统计学意义（F=21.033，P<0.01）。结论：老年急性冠脉综合征患者衰弱水平较高，年龄、运动习惯、自理能力、吸烟、多病共存、TC、Hb、Alb、WBC是老年急性冠脉综合征患者PCI术后衰弱的影响因素，及时评估并识别患者衰弱状态，及早进行干预以预防或降低老年急性冠脉综合征患者衰弱现状至关重要

关键词: 急性冠脉综合征, 经皮冠状动脉介入术, 衰弱, 影响因素