Abstract: Objective: To investigate the subjective well-being of postoperative chemotherapy patients with colorectal cancer and analyze its influencing factors. Methods: A total of 215 patients with colorectal cancer undergoing postoperative chemotherapy were investigated by the general information questionnaire, the general well-being schedule, the simplified coping style questionnaire, the event related rumination inventory, and the Rosenberg self-esteem scale. Results: The total score of subjective well-being in patients with postoperative chemotherapy for colorectal cancer was 69.72±13.67. The results of multiple stepwise regression showed that positive coping, negative coping, self-esteem and invasive meditation were the main influencing factors of subjective well-being in patients with postoperative chemotherapy for colorectal cancer (adjusted R²=0.761, P<0.001). Conclusion: It is urgent to improve the subjective well-being of patients undergoing postoperative chemotherapy for colorectal cancer. In clinical work, medical staff should guide them to actively cope with the disease and help them to regulate negative emotions and improve subjective the well-being.

Key words: Colorectal cancer, Subjective well-being, Coping style, Rumination, Influencing factors

摘要： 目的：探讨结直肠癌术后化疗患者主观幸福感现状并分析其影响因素。方法：应用横断面研究方法，对215例结直肠癌术后化疗患者，使用一般资料调查表、总体幸福感量表、简易应对方式问卷、事件相关反刍性沉思问卷和Rosenberg自尊量表进行调查。结果：215例结直肠癌术后化疗患者主观幸福感总分为（69.72±13.67）分。多元逐步回归分析结果显示，积极应对、消极应对、自尊、侵入性沉思是结直肠癌术后化疗患者主观幸福感的主要影响因素（调整R²=0.761，P＜0.001）。结论：结直肠癌术后化疗患者主观幸福感水平亟待提高，临床工作中医护人员应正确引导患者积极应对疾病，帮助患者调节不良情绪，以提高其主观幸福感。

关键词: 结直肠癌, 主观幸福感, 应对方式, 反刍性沉思, 影响因素